PSA total
Prostate specific antigen (PSA) is a single-chain glycoprotein. Pathologically increased production of PSA is typical marker of malignant prostatic tissues and of bone metastases of prostatic origin. Increased levels of PSA are found also in patients with prostate benign hyperplasia. The determination of PSA can be used in diagnosis, prognosis and monitoring of prostate cancer. In combination with free PSA, it is used for differential diagnosis between prostate cancer and benign prostate hyperplasia.