Anti-IA2
Three major antigens of Langerhans’ islets of pancreatic β-cells are glutamic acid decarboxylase (GAD), insulinoma-associated protein 2 (IA-2) and insulin. The determination of circulating autoantibodies against these structures are used for specific classification in diabetes mellitus type I and LADA, as well as for diabetes prediction in first grade relatives of diabetic mellitus type I patients. Prevalence of Anti-IA2 in DM type I patients is 50-85%.
| Name |
Anti-IA2 ELISA |
| Ref. | C15994 |
| Method | ELISA |
| Tests | 12x8 |
| Enzyme | Horseradish peroxidase |
| Detection | Absorbance at 450 and 405 nm |
| Sensitivity | 0.95 U/mL |
| Incubation conditions | 16-20 hrs/2-8°C+1 hr/2-8°C+20 min/RT;SH+20 min/RT |
| Calibrator range | 0;7.5-4000 U/mL |
| Sample volume (μL) | 50 |
| Sample form | serum |
| Analyte info |  |
| Instructions for Use | |
| MSDS | |