Three major antigens of Langerhans’ islets of pancreatic β-cells are glutamic acid decarboxylase (GAD), insulinoma-associated protein 2 (IA-2) and insulin. The determination of circulating autoantibodies against these structures are used for specific classification in diabetes mellitus  type I and LADA, as well as for diabetes prediction in first grade relatives of diabetic mellitus type I patients. Prevalence of Anti-GAD in DM type I patients is 70-90%.

Ref. C15995
Method ELISA
Tests 12x8
Enzyme Horseradish peroxidase
Detection Absorbance at 450 and 405 nm
Sensitivity 0.57 U/mL
Incubation conditions 2x1 hr/RT;SH+20 min/RT+20 min/RT
Calibrator range 0;5-2000 U/mL
Sample volume (μL) 25
Sample form serum
Analyte info                      
Instructions for Use