Anti R-TSH
The determination of circulating anti-TSH receptor autoantibodies (anti-rTSH) is useful in the diagnosis and follow-up of Graves¢ disease. It is also helpful in the investigation of neonatal thyrotoxicosis.
Circulating anti-TSH receptor autoantibodies (anti-rTSH) is a group of related immunoglobulins that bind to thyroid cell membranes at or near the TSH-receptor. In general, these antibodies demonstrate substantial heterogenity. Some anti-rTSH cause thyroid stimulation, whereas others decrease thyroid secretion via blocking of TSH action, and third type of anti-rTSH has no effect on thyroid secretion activity. The presence of anti-rTSH is typical for Graves¢ disease, bat may appear in other autoimune thyroid disorders, too.
| Name | RRA Anti R-TSH |
| Ref. | A15728/A54464 |
| Method | RRA |
| Type | Coated tubes |
| Tests | 60/100 |
| Max. Activity (kBq) | 100/180 |
| Sensitivity | 0.33 U/L |
| Incubation conditions | 2 hrs+1 hr/RT;shaking |
| Calibrator range | 0;1-40 U/L |
| Sample volume (μL) | 100 |
| Sample form | serum |
| Analyte info |  |
| Instructions for Use | |
| MSDS | |