Anti-Insulin

Three major antigens of Langerhans’ islets of pancreatic β-cells are glutamic acid decarboxylase (GAD), insulinoma-associated protein 2 (IA-2) and insulin. The determination of circulating autoantibodies against these structures are used for specific classification in diabetes mellitus  type I and LADA, as well as for diabetes prediction in first grade relatives of diabetic mellitus type I patients. Prevalence of Anti-insilin in DM type I patients is 30-50%, in children around 70 %.

Name	IRMA Anti-Insulin
Ref.	A36473/A36474
Method	IRMA
Type	Homogenous phase
Tests	50/100
Max. Activity (kBq)	40/2x40
Sensitivity	0.032 U/mL
Incubation conditions	16-24 hrs/RT+1 hr/2-8°C
Calibrator range	0;0.5-50 U/mL
Sample volume (μL)	20
Sample form	serum
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MSDS