TPS® – tissue polypeptide antigen specific assay determines soluble fragments of Cytokeratin 18, containing defined epitope recognized by antibody M3, in human serum. The size of the determined cytokeratin fragments is in the range of 10-500 kDa. It is used as a marker of tumor activity reflecting malignant tissue degradation and cell necrosis in epithelial cell carcinomas, particularly in breast cancer (in combination with CA 15-3), prostate cancer (in combination with PSA) and ovarian cancer (in combination with CA125.


Ref. C75247
Method ELISA
Tests 12x8
Enzyme Horseradish peroxidase
Detection Absorbance at 450 nm
Sensitivity (LoD) 10.4 U/L
Incubation conditions 2x1 hr/RT;shaking+20 min/RT+1 min/RT;shaking
Calibrator range 0;30-1 200 U/L
Sample volume (μL) 50
Sample form serum
Analyte info        
Instructions for Use