NSE
Enolase is a glycolytic enzyme participating in the metabolism of glucose. Neuron specific isoform of the enolase (Neuron specific enolase - NSE) is found in neuronal tissue and in the cells of the diffuse neuroendocrine system, the amine precursor uptake and decarboxylation (APUD) tissue, and its concentration increases in some benign lung diseases and liver diseases, as well as in malign tumors of neuroendocrine origin. The determination of NSE can be used in prognosis, diagnosis and monitoring of neuroendocrine tumor (NET) and small cell lung carcinoma (SCLC).