NSE
Enolase is a glycolytic enzyme participating in the metabolism of glucose. Neuron specific isoform of the enolase (Neuron specific enolase - NSE) is found in neuronal tissue and in the cells of the diffuse neuroendocrine system, the amine precursor uptake and decarboxylation (APUD) tissue, and its concentration increases in some benign lung diseases and liver diseases, as well as in malign tumors of neuroendocrine origin. Determination of NSE in serum is used in the management of patients with suspected or diagnosed small cell lung carcinoma or neuroblastoma to confirm the diagnosis, to control the effect of the treatment, and to detect recurrent disease.