MonoTotal® assay determines soluble fragments of cytokeratin 19, 8 and, at certain extent, cytokeratin 18 in serum. The size of the determined cytokeratin fragments is in the range of 10-500 kDa. It is used as a marker of tumor activity reflecting malignant tissue degradation and cell necrosis in epithelial cell carcinomas, particularly in Non-small cell lung cancer.


Name MonoTotal® IRMA KIT
Ref. C52721
Method IRMA
Type Coated beads
Tests 100
Max. Activity (kBq) 814
Sensitivity (LoD) 17.9 U/L
Incubation conditions 2 hrs/RT;shaking
Calibrator range 0; 1.50-6000 U/L
Sample volume (μL) 100
Sample form serum
Analyte info                      
Instructions for Use