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  • Estrone

    Apr 21 2014 5:17 PM

    Estrone (E1) is one of the three major naturally-occurring estrogens. It is principal estrogene in women after menopause, when ovarian production of estradiol ceases. The determination of estrone can be used in the assessment of fertility status and sexual development. It can be used in monitoring hormone replacement therapy in postmenopausal women. It can be also useful as an aid in diagnosis of precocious and delayed puberty in girls and as an aid in diagnosis of disorders of sex steroid metabolism (e.g. aromatase deficiency and 17α-hydroxylase deficiency).

    Name Estrone RIA
    Ref. DSL8700
    Method RIA
    Type Coated tubes
    Tests 100
    Max. Activity (kBq) 185
    Sensitivity (LoD) 10 pg/mL
    Incubation conditions 1 hr/RT;shaking (optional 2 hrs/RT;shaking)
    Calibrator range 0;16- 2000 pg/mL
    Sample volume (μL) 50 (optional 200)
    Sample form serum; plasma
    Analyte info                      
    Instructions for Use         
    MSDS                              

  • Estrone Sulfate

    Apr 21 2014 5:22 PM

    Estrone sulfate (E1-S) is a sulfate derivative of estrone, and is the most abundant form of circulating estrogens in both men and non-pregnant women.

    Estrone sulfate itself does not have direct estrogenic activity, it may be considered rather as a slowly-metabolized estrogen reservoir. The determination of estrone sulfate, as a marker of global estrogenic activity, can be used for monitoring of hormone replacement therapy in postmenopausal women.

    Name Estrone Sulfate RIA
    Ref. DSL5400
    Method RIA
    Type Homogenous phase
    Tests 100
    Max. Activity (kBq) 185
    Sensitivity 0.01 ng/mL
    Incubation conditions 3 hrs/RT;shaking+15 min/RT
    Calibrator range 0;0.05-80 ng/mL
    Sample volume (μL) 100
    Sample form serum; plasma
    Analyte info                      
    Instructions for Use         
    MSDS