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  • Estradiol

    Apr 21 2014 4:48 PM

    Estradiol is a steroid hormone synthesized by the gonads. In women, it plays an important role in the functioning of the menstrual cycle and the triggering of ovulation. The determination of estradiol can be used for the assessment of fertility status and sexual development. In females, it can be used in differential diagnosis of amenorrhea and other causes of female infertility and in monitoring of ovulation status. It can be also used as an aid in diagnosis of precocious and delayed puberty in children. In males, it can be used as an aid in diagnosis of feminizing syndromes, including gynecomastia. It can be also used in monitoring patients on hormone replacement and antiestrogen therapy.

    We offer two different formats of this assay, see tables below:

    Name RIA Estradiol
    Ref. B89462/A21854
    Method RIA
    Type Coated tubes
    Tests 50/100
    Max. Activity (kBq) 185
    Sensitivity (LoD) 10.4 pg/mL
    Incubation conditions 3 hrs/RT;shaking
    Calibrator range 0;15-4320 pg/mL
    Sample volume (μL) 100
    Sample form serum; plasma
    Analyte info                      
    Instructions for Use         
    MSDS                              
    Reagents supplied separately Estradiol diluent (10 mL), Ref. IM1863

     

     

    Name Ultra-Sensitive Estradiol RIA
    Ref. DSL4800
    Method RIA
    Type Homogenous phase
    Tests 100
    Max. Activity (kBq) 185
    Sensitivity 2.2 pg/mL
    Incubation conditions 1 hr+2 hrs+20 min/RT
    Calibrator range 0;5-750 pg/mL
    Sample volume (μL) 200
    Sample form serum; plasma
    Analyte info                      
    Instructions for Use         
    MSDS                              
    Reagents supplied separately Estradiol + alpha Subunit diluent (2 mL), Ref. B64533

  • Estrone

    Apr 21 2014 5:17 PM

    Estrone (E1) is one of the three major naturally-occurring estrogens. It is principal estrogene in women after menopause, when ovarian production of estradiol ceases. The determination of estrone can be used in the assessment of fertility status and sexual development. It can be used in monitoring hormone replacement therapy in postmenopausal women. It can be also useful as an aid in diagnosis of precocious and delayed puberty in girls and as an aid in diagnosis of disorders of sex steroid metabolism (e.g. aromatase deficiency and 17α-hydroxylase deficiency).

    Name Estrone RIA
    Ref. DSL8700
    Method RIA
    Type Coated tubes
    Tests 100
    Max. Activity (kBq) 185
    Sensitivity (LoD) 10 pg/mL
    Incubation conditions 1 hr/RT;shaking (optional 2 hrs/RT;shaking)
    Calibrator range 0;16- 2000 pg/mL
    Sample volume (μL) 50 (optional 200)
    Sample form serum; plasma
    Analyte info                      
    Instructions for Use         
    MSDS                              

  • Alpha-Subunit

    May 1 2014 8:19 PM

    Thyrotropin (TSH), human follicle stimulating hormone (FSH), human luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are glycoprotein hormones. They are composed of two distinct, non-covalently bound subunits: a and ß. The a-subunits of TSH, LH, FSH and hCG are immunologically identical. Certain amount of free a-subunit is found under normal conditions in the circulation. The determination of a-subunit can be used in diagnosis and monitoring of pituitary tumors.

    Name IRMA alpha-Subunit
    Ref. IM1186
    Method IRMA
    Type Coated tubes
    Tests 100
    Max. Activity (kBq) 370
    Sensitivity (LoD) 0.11 IU/L
    Incubation conditions 1 hr/RT;shaking
    Calibrator range 0;0.25-10 IU/L
    Sample volume (μL) 100
    Sample form serum; plasma
    Instructions for Use         
    MSDS                              
    Reagents supplied separately Estradiol + alpha Subunit diluent (2 mL), Ref. B64533